IVF department
Sirvan IVF Clinic is located on the fifth floor of Madaran Hospital and is ready to serve dear people with the establishment of infertility clinic and andrology laboratory.
This center has a staff consisting of gynecologists with infertility fellowship, urologist, reproductive health and sexual health and an experienced embryology team.
Services of the IVF clinic of Motharan Hospital
Services of the IVF clinic of Mother Hospital
Infertility treatment
IUI intrauterine insemination
Microinjection IVF
Fertility preservation
Fertility services
Pregnancy and women’s health services
Diagnostic and treatment services for recurrent miscarriage
Specialized services for men
Men’s specialized surgeries
PSG and PGD sex determination
Embryo hatching
Donated eggs and embryos
Freezing testicular and ovarian tissue
Embryo, egg and sperm freezing
laparoscopy
hysteroscopy
Reproductive health and sexual health counseling
Fertility Preservation
The survival rate after cancer has increased significantly in recent decades. However, these treatments also have disadvantages, and patients (or parents in the case of children) should be informed of the long-term complications of oncological treatments and possible options for fertility preservation in these patients. In oncological patients, two special situations often arise: short time to stimulate ovulation and the need not to reach high levels of estradiol. In using embryo freezing methods to preserve the fertility of cancer patients, it is very important to know the couple’s preference for disposal of unused embryos. Until now, embryo freezing has been the only clinically accepted method to preserve the fertility of cancer patients before chemotherapy and/or radiotherapy. The pregnancy rate after thawing is acceptable and depending on the number of available embryos and their quality, it is around 30% per transfer of frozen embryos.
Experimental methods of preserving male fertility and treating male factor infertility
Infertility is a common disease that has insidious effects on infertile individuals, their families, and society that go far beyond the inability to have biological children. Lifestyle changes, infertility treatments, and assisted reproductive technology (ART) are available to help many infertile couples achieve their fertility goals. All of these technologies require that the infertile individual be able to produce at least a small number of functional gametes (eggs or sperm). It is not possible for a person who does not produce gametes to have a biological child. This review focuses on the infertile male and describes several stem cell-based methods and gene therapy approaches that are under investigation and may lead to new fertility treatment options for men with azoospermia.
What do you mean by fertility preservation?
A method used to help preserve a person’s ability to have children. In fact, it is a method of maintaining fertility, which is performed before the start of medical treatment for some diseases that may cause infertility, such as radiation therapy or chemotherapy.
Fertility preservation for women
Fertility preservation using tamoxifen and letrozole in a trial of estrogen-sensitive tumors. Letrozole plus gonadotropin and tamoxifen plus gonadotropin are currently used for fertility preservation in patients with estrogen receptor-positive breast cancer, it is unclear which of the two may lead to improved oocyte function.
Serum biomarkers to determine treatment effects on ovarian reserve in postmenopausal women with breast cancer or mutations.
Ovarian tissue freezing. The study hopes to help develop ovarian tissue freezing and thawing technologies to preserve fertility. The study is open to women undergoing cancer treatment or surgery, or women who have an inherited mutation and are considering risk-reducing surgery.
Fertility preservation for men
Freezing testicular tissue to preserve fertility. Testicular tissue freezing is an experimental procedure in which testicular tissue is recovered and frozen. This technique is intended for young male patients, with the goal that their tissue may be used to restore fertility in the future, when experimental techniques come out of the research pipeline. It is explained in detail on the page related to the type of service.
Infertility Treatment
Infertility is when a couple cannot conceive despite having regular unprotected sex.
1 out of every 7 couples may have difficulty conceiving. About 84% of couples conceive naturally within a year if they have regular unprotected sex (every 2 or 3 days).
For couples who have been trying to conceive for more than 3 years without success, the chance of getting pregnant naturally in the next year is 1 in 4 or less.
Getting help
Some people get pregnant quickly, but for others it may take longer. If you do not get pregnant after a year of trying, it is better to see a specialist doctor.
Women 36 years of age and older, and anyone who already knows they may have fertility problems, should see their health care provider early.
They can investigate common causes of fertility problems and suggest treatments that can help.
Infertility is usually diagnosed when a couple fails to conceive after a year of trying.
There are 2 types of infertility
Primary Infertility: It is about a person who has never had a child in the past and now has trouble getting pregnant.
Secondary infertility: It is about a person who has been pregnant 1 or more times in the past, but now has trouble getting pregnant again.
Infertility treatment
Infertility treatments include
Medical treatment for irregular ovulation: surgical procedures such as treating endometriosis, repairing the fallopian tubes, or removing scarring (adhesions) in the uterus or abdominal cavity.
Assisted fertilization such as intrauterine insemination (IUI) or IVF.
The treatment offered depends on what is causing the fertility problems and what services are available at the clinic you visit.
It is important to choose a private clinic carefully. You can ask a general practitioner for advice and you should make sure that you choose a clinic that is licensed by the Ministry of Health.
While infertility treatment is promising, some infertility treatments such as IVF can cause complications.
Multiple pregnancy
If more than 1 embryo is placed in the uterus as part of IVF treatment, the chance of twins increases. This may not sound like a bad thing, but it significantly increases the risk of complications for you and your babies.
Ectopic pregnancy
If IVF is performed, the risk of ectopic pregnancy increases slightly.
What causes infertility?
There are many possible causes of infertility, and fertility problems can affect either partner. But in a quarter of cases, the cause cannot be identified.
Common causes of infertility include:
Lack of regular ovulation (monthly egg release)
low quality semen
Blocked or damaged fallopian tubes
Endometriosis: where the tissue that acts like the inner lining of the uterus (endometrium) is found outside the uterus.
Risk factors
There are also several factors that can affect fertility, including:
Age: Fertility decreases with age.
Weight: Being overweight or obese (having a BMI of 30 or more) reduces fertility. In women, being overweight or severely underweight can affect ovulation.
Sexually transmitted infections (STIs): Several sexually transmitted diseases, including chlamydia, can affect fertility.
Smoking: Can affect fertility Smoking (including passive smoking) affects your chances of getting pregnant and can reduce the quality of semen.
Alcohol: The safest way is not to drink alcohol at all to minimize the risks to your baby. Drinking too much alcohol can also affect sperm quality.
Environmental factors: Exposure to certain pesticides, solvents, and metals has been shown to affect fertility, especially in men.
Stress: It can affect your relationship with your partner and cause a decrease in sex drive. In severe cases, stress may also affect ovulation and sperm production.
There is no evidence that caffeinated beverages such as tea, coffee, and cola are associated with fertility problems.
Causes of infertility
Infertility can be caused by many reasons. For 1 out of 4 couples, the cause cannot be identified.
Infertility in women
Infertility is usually caused by problems with ovulation (the monthly release of an egg from the ovaries).
Some problems stop the egg from being released altogether, while others prevent the egg from being released during some cycles but not others.
Ovulation problems can be caused by:
polycystic ovary syndrome (PCOS)
Thyroid problems: Both hyperthyroidism and hypothyroidism can prevent ovulation.
Premature ovarian failure: where the ovaries stop working before the age of 40.
Scars from surgery
Pelvic surgery can damage and scar the fallopian tubes that connect the ovaries to the uterus.
Cervical surgery can also sometimes cause scarring or shortening of the cervix (cervix).
Cervical mucus problems
When you’re ovulating, the lining of your cervix becomes thinner so that sperm can swim through it more easily. If there is a problem with the mucus, it can make it more difficult to get pregnant.
Fibroids
A non-cancerous growth called a fibroid in or around the uterus can affect fertility. In some cases, they may prevent a fertilized egg from attaching to the uterus or may block the fallopian tube.
endometriosis
Endometriosis is a condition in which small pieces of the lining of the uterus (endometrium) start to grow in other places, such as the ovaries. It can damage the ovaries or fallopian tubes and cause fertility problems.
Pelvic inflammatory disease
Pelvic inflammatory disease (PID) is an infection of the female upper reproductive tract, which includes the uterus, fallopian tubes, and ovaries. It is often caused by a sexually transmitted infection (STI). PID can damage the fallopian tubes, causing them to become sore and making it impossible for the egg to move into the uterus.
sterilization
Some women who no longer intend to have children choose sterilization. Sterilization involves blocking the fallopian tubes so that the egg cannot reach the uterus. It is rarely reversible, so you will not necessarily be able to have a baby by doing a sterilization reversal.
Medicines and drugs
Side effects of some types of drugs and drugs can affect your fertility. This includes:
Nonsteroidal anti-inflammatory drugs (NSAIDs): Long-term or high-dose use of NSAIDs, such as ibuprofen or aspirin, can make it more difficult to get pregnant.
Chemotherapy: The drugs used for chemotherapy can sometimes cause ovarian failure, which means your ovaries can no longer work properly.
Neuroleptics: Antipsychotic drugs, often used to treat psychosis, can sometimes cause amenorrhea or infertility.
Spironolactone is a type of medicine used to treat fluid retention (edema). Fertility should usually improve about 2 months after discontinuing spironolactone.
Illicit drugs such as marijuana and cocaine can seriously affect fertility and make ovulation more difficult.
Infertility in men
semen and sperm
One of the common causes of infertility in men is poor quality semen (liquid containing sperm) that is ejaculated during sex.
Possible causes of abnormal sperm include:
1. Lack of sperm: You may have very low sperm count or no sperm at all.
2. Sperms that don’t move properly: This makes it harder for the sperm to swim towards the egg.
3. Abnormal sperm: Sperm can sometimes be abnormally shaped, making it harder for them to move and fertilize an egg.
Many cases of abnormal semen are unexplained.
There is a link between increased scrotal temperature and decreased semen quality, but it is unclear whether wearing loose underwear improves fertility.
testicles
The testicles produce and store sperm. If they are damaged, it can seriously affect the quality of your semen.
Damage to the testicles can occur as a result of:
Infection of your testicles.
testicular cancer
Testicular surgery.
A problem with your testicles that you were born with (birth defect): when one or both testicles have not descended into the scrotum (the loose sac of skin that contains your testicles) (undescended testicles).
Damage to your testicles.
Sterilization: Some men choose a vasectomy if they do not want a child or more children.
This involves cutting and sealing off the tubes that carry sperm from your testicles (epididymal death) so that your semen no longer contains sperm. A vasectomy can be reversed, but reversals are usually not successful.
Ejaculation disorders: Some men experience ejaculation problems, which can make it difficult to release semen during sex (ejaculation).
Hypogonadism: Hypogonadism is an abnormally low level of testosterone, the male sex hormone involved in sperm production. Hypogonadism may be caused by a tumor, illegal drug use, or Klinefelter syndrome (a rare syndrome involving an extra female chromosome).
Medicines and drugs: Certain types of drugs can sometimes cause infertility problems. This includes:
Sulfasalazine is an anti-inflammatory drug used to treat diseases such as Crohn’s disease and rheumatoid arthritis. Sulfasalazine can lower sperm count, but the effects are temporary and your sperm count should return to normal when you stop taking it.
Anabolic steroids: Often used illegally to build muscle and improve athletic performance. Long-term abuse of anabolic steroids can reduce sperm count and sperm motility.
Chemotherapy: Drugs used in chemotherapy can sometimes severely reduce sperm production.
Herbal medicines: Some herbal medicines, such as the root extract of the Chinese plant Tripterygium wilfordii, can affect sperm production or reduce the size of your testicles.
Illegal drugs such as marijuana and cocaine can also affect semen quality.
intrauterine insemination
intrauterine insemination (IUI) is a type of artificial insemination and a method of treating infertility. In this procedure, washed and concentrated sperm are placed directly into your uterus when your ovary releases one or more eggs for fertilization.
intrauterine insemination (IUI) treatment
During an intrauterine insemination (IUI) procedure, sperm are placed directly into the uterus using a small catheter. The purpose of this treatment is to improve the chance of conception by increasing the number of healthy sperm that reaches the fallopian tubes when the woman is most fertile.
IUI can be useful for:
Couples experiencing infertility due to medical conditions (such as endometriosis or low sperm count and quality).
Couples with unexplained infertility.
IUI is a widely used treatment option because it is a minimally invasive and low-cost alternative to in vitro fertilization (IVF) and can be easily performed in our clinic.
What to expect in IUI treatment:
At your initial consultation, you’ll meet with one of our fertility specialists to go over your medical history and family planning goals. We will then order diagnostic tests such as a saline infusion ultrasound (SIS) or hysterosalpingogram (HSG) to make sure your fallopian tubes are open and your uterus looks normal. This information is important to help us know which infertility treatment is best for you.
IUI treatment is performed during the ovulation cycle. Usually, patients use fertility drugs such as Clomid to stimulate ovulation. We prescribe your medications and monitor you closely with regular ultrasounds and blood tests to determine the best time for your insemination procedure.
Once your ovulation window is determined, your partner provides a sperm sample to our andrologists, then we perform a special procedure called sperm washing on the samples in the laboratory to obtain the best sperm quality.
Your IUI treatment will be done at the Sirvan infertility treatment center and at the IUI treatment clinic. During this procedure, the doctor first inserts a speculum to view the cervix (opening to the uterus), somewhat like performing a Pap smear. Next, we insert a small catheter (designed specifically for IUI) to place the final sample of semen into your uterus. The process only takes a few minutes and is generally painless. Some women experience mild cramping during the procedure and spotting one to two days after the procedure. After the operation, you can return to your normal daily activities, including intercourse.
Two weeks after IUI, you will take a pregnancy test to check if the procedure was successful. If you are pregnant, we will closely monitor your pregnancy through blood tests and ultrasounds. If you test negative, we will prepare for a new treatment cycle or consider other treatment options.
What is the difference between IUI and IVF?
Through intrauterine insemination (IUI), sperm are inserted directly into the uterus using a speculum. Through in vitro fertilization (IVF), eggs are surgically removed using a needle passed through the back of the vagina, and those eggs are fertilized outside the body.
How long does it take to get pregnant with IUI?
How long does it take to get pregnant using IUI? Since the insemination is done during ovulation, it takes approximately two weeks after the procedure to determine if the treatment was successful after a positive pregnancy test.
What are the chances of pregnancy with IUI?
Pregnancy can occur, but the success rate depends on the location of the blockage. If the blockage is near the ovary, the success rate of IUI is 11.7%. If it is close to the uterus, the chance of success is about 38.1%. If the intended father experiences male factor infertility, the success rate of IUI is about 16.9%.
How does IUI help pregnancy?
IUI works by placing sperm cells directly into your uterus at the time of ovulation, helping the sperm get closer to your egg. This reduces the time and distance the sperm must travel and makes it easier to fertilize the egg.
How painful is the IUI procedure?
IUI is minimally invasive and patients do not even need sedation or anesthesia during the treatment. Patients may experience a mild pinching experience (similar to that experienced during a routine Pap smear test) and some cramping as the catheter passes through the cervix.
Can you choose the gender with IUI?
Microsort is the only method for sex selection IUI intrauterine insemination. Many clinics offer sperm selection by weight, also known as the Erickson method, but this method cannot be compared to micro-sorting technology.
Microinjection IVF
Step by step IVF
On this page you will read:
Start with IVF
Preparation before treatment
IVF injection
Egg retrieval process
Sperm collection
Fetal development
Embryo transfer
freezing
Pregnancy test and pregnancy follow-up
Find a fertility specialist
Resources for IVF patients
Start with IVF
IVF in vitro fertilization step by step:
As a patient at Sirvan Fertility Medicine Center, you can expect to receive the highest quality of care for IVF treatment. Before starting IVF, you will go through a fertility evaluation process. Once you’ve completed that and you and your specialist have decided that IVF is the next step in your fertility journey, you’ll go through the following steps:
Preparation before treatment
IVF injection
Egg retrieval process
Sperm collection
fetal growth
Embryo transfer
Pregnancy test and pregnancy follow-up
Preparation before treatment
Calendar Cycle and Schedule: At the time of your first treatment visit, we ask you to complete the following:
Pre-pregnancy screening tests
Evaluation of the uterine cavity
Consider preconception genetic carrier screening
Sperm analysis (if not already done)
Our nurses will help you plan these things. Our nurses will also create a calendar for your entire course.
IVF injection
Preparation for egg retrieval with IVF injection
The IVF egg retrieval process begins with your doctor prescribing a series of medications (usually ampoules) that help your ovaries produce multiple mature eggs at the same time. Retrieving multiple eggs increases your chances of success because not all eggs are fertilized or develop normally after fertilization. Before starting medications to stimulate the ovaries to produce eggs, your doctor will measure your uterine lining. And the ovaries will be examined for possible follicles or cysts. If the ultrasound is normal, a nurse will check your individual calendar and confirm when you can start medications to stimulate egg growth.
What can you do to improve the quality of your eggs?
To improve the health of your eggs, we recommend a healthy, balanced diet that limits the amount of highly processed foods. We also recommend moderate exercise and a healthy lifestyle.
However, when you start your IVF injections, it’s important not to exercise too much, as this medicine will enlarge your ovaries and too much exercise can twist the ovaries and cut off blood flow.
IVF egg retrieval process
Once your doctor determines that your eggs are ready for retrieval, you will be given another medication (HCG) or (Lupron) 36 hours before the retrieval procedure. This medicine will bring your eggs to final maturity.
The recovery process (puncture) is a short procedure of 15 to 30 minutes that is performed in the operating room. During egg retrieval, using an ultrasound machine, the doctor uses an ultrasound-guided needle to gently remove your eggs from your ovaries. Your doctor will sedate you with an IV during the procedure and you should have little or no discomfort. Because of the anesthesia, you will need to stay in the clinic for an hour to be monitored before going home. You need it to take you home. You should take a full day off from work to rest and recover.
Recovery after egg retrieval
While the procedure is relatively simple, you may experience some pain after IVF egg retrieval, including cramping and a feeling of fullness or pressure. You should also give your body time to rest and heal after the procedure. We advise you to refrain from vigorous physical activity and sexual intercourse for approximately two weeks.
Side effects of egg retrieval
Side effects after egg retrieval can include the following:
mild cramps
Mild bloating
constipation
Breast tenderness
These are all common side effects after egg retrieval and are nothing to worry about. More severe symptoms include:
hip pain
Blood in the urine or heavy vaginal bleeding
Painful urination
Fever over 38 degrees Celsius
If any of these symptoms occur, please contact your doctor immediately.
Does egg retrieval harm your remaining eggs?
Not at all, the process is well-monitored and non-invasive. After the egg retrieval procedure, the doctor will also perform a vaginal examination to make sure that there is no problem or uterine bleeding.
After egg retrieval
During egg retrieval, your doctor extracts follicular fluid from your ovaries. Eggs are released from your ovaries with follicular fluid. One of our technicians will be with your doctor to help you during the procedure. We will collect the follicular fluid in a test tube. We then transfer the follicular fluid to the embryo lab, where one of our embryologists extracts the eggs in a container with specialized media. Then we incubate your eggs in specialized environments so that they can be fertilized and become embryos.
Repeated Abortion Clinic
Recurrent miscarriage refers to cases where the miscarriage has been repeated spontaneously and at least two to three times in a row. Women who have 2 consecutive spontaneous abortions or 2 failed embryo transfers will be candidates for introduction to the repeated abortion treatment clinic.
The frequent abortion clinic of Sirvan infertility treatment center has been established with the aim of providing specialized services to those pregnant mothers with high-risk pregnancies who need special care. The specialists in this clinic, using the most advanced equipment and according to current knowledge, are trying to help pregnant mothers pass this critical period safely and with minimal complications and have a healthy baby. In case of failure of the treatment, the matter will be examined in the specialized team of recurrent miscarriage treatment, including specialists in obstetrics, gynecology, immunology, embryology, and genetics, with the presence of the couple, and a suggested treatment will be provided.
The reasons for frequent miscarriage are very diverse and include:
Hormonal and genetic disorders
Immune system disorders
infection
Blood coagulation disorders
Structural abnormalities of the reproductive system
Cervical insufficiency, if detected, some of them can be treated.
Other factors: Factors such as phospholipid deficiency syndrome, blood sugar disease, thrombosis, smoking, and the presence of some type of antibody in the mother’s body.
The target group of this clinic:
Mothers with chronic diseases such as preeclampsia and eclampsia
Mothers at risk of miscarriage or premature birth
Mothers with multiple pregnancies
Elderly mothers
Mothers who have a history of repeated miscarriages
Mothers who have had a history of unsuccessful ICSI/IVF cycles
Mothers who have a history of giving birth to a baby with abnormalities
Recurrent miscarriage treatment
Treatments for recurrent miscarriage can include lifestyle changes, medications, surgery, or genetic testing to increase the chances of a successful pregnancy.
If you have experienced repeated miscarriages
Gynecologists are generally familiar with these issues and know which tests to perform. However, if the initial tests show nothing, you may be advised to see a reproductive endocrinologist.
Ways to diagnose recurrent miscarriage
Blood tests
Ultrasound
Genetic screening
Hormonal tests
Histogram
hysteroscopy
Endometrial biopsy
When does recurrent miscarriage need to be investigated?
Fortunately, most women will have a successful pregnancy even after two miscarriages. However, if you’ve had three or more early miscarriages in a row or one miscarriage after 12 weeks, talk to your doctor about getting an investigation.
Does IVF help treat recurrent miscarriage?
Three or more miscarriages occur in less than 1% of women. The good news is that in vitro fertilization (IVF) with genetic testing can significantly reduce the risk of miscarriage and increase the chances of a successful pregnancy.
Referral time for recurrent miscarriage treatment
Anyone who has experienced two or more miscarriages should see a reproductive specialist.
RPL test
RPL testing is performed by taking a small sample of POC and checking for chromosomal abnormalities using standard techniques such as karyotyping and fluorescence in situ hybridization. (FISH).
Can an endocrinologist help with abortion?
Once diagnosed, doctors should refer patients to an endocrinologist, preferably one who specializes in preconception and pregnancy. While some miscarriages remain unexplained, doctors have many diagnostic tools at their disposal.
Drug treatment after abortion
If not all of the tissue comes out, a condition known as an incomplete miscarriage, you may need treatment to stop the bleeding and prevent infection. The most common procedure is dilation and curettage (D&C), which involves dilating the cervix and scraping away the lining of the uterus, or endometrium.
Treatment in repeated abortion clinic
If you have had repeated miscarriages, you may be offered a blood test and/or pelvic ultrasound to identify the cause. At Sirvan Recurrent Miscarriage Clinic, we evaluate your blood tests to check the cause of the possibility of repeated miscarriage. Recurrent pregnancy loss (RPL) affects 0.8 to 1.4% of couples and this prevalence increases with age. finds However, the cause is usually unknown, and most treatments are not supported by strong evidence. There are many tests that look for the causes of RPL:
Hormonal status
Sperm morphology and DNA fragmentation
Immunological status
Evaluation of the uterus
Thrombophilia, etc.
Recently, many types of treatment have appeared, most of which do not have good evidence. For example, we can mention the use of anticoagulants, aspirin, corticosteroids, progesterone, antioxidants, and emotional support for couples. It is argued that some methods, such as preimplantation genetic testing for aneuploidy and intracytoplasmic sperm injection, which are morphologically selected, influence the results and contribute to the treatment of RPL.
Sex determination by IVF method
PGD method includes genetic examination and diagnosis of possible embryo disorders before implantation. PGD is used in the investigation of single-gene disorders (molecular PGD), chromosomal abnormalities, pre-implantation screening (PGS), and is also considered the most accurate and complex technique for sex selection. In the PGD method, in vitro fertilization (IVF/ICSI) is takes, by stimulating the ovary, the woman’s eggs are collected and combined with the man’s sperm in the laboratory and an embryo is formed. On the third day of fertilization, when the embryo has between six and eight cells, a small laser cut is made in the embryo’s cell membrane and one of the cells is removed. to be damaged, separates from the other cells. Removing one of these cells does not harm the developing embryo. Each cell in the embryo contains an identical copy of the embryo’s genome It is checked through one of two molecular or cytological methods, and healthy embryos are placed in the mother’s womb.
In the PGD method, by selecting a genetically healthy embryo, the formation and birth of a baby with genetic abnormalities or chromosomal disorders is prevented. On the other hand, an incision made with a laser to check the fetal cells in the fetal membrane (zona pellucida) helps the embryo to implant in the uterus better. The uterus is implanted. At this stage, one should wait for implantation and a positive pregnancy test. Embryos that do not have any genetic problems will be frozen for later use. Meanwhile, the defective embryos will be destroyed. The test process will last about two weeks, which includes the following steps:
Collection of sperm and egg samples from couples
fertility (microinjection)
Three to five days of time for the growth and development of the embryo
One to two weeks to do the test and review the results.
Finally, the embryo with the desired sex will be implanted in the uterus.
Who can benefit from PGD?
One of the most important advantages of doing this test is that it will prevent the transmission of any disease or genetic disorder to the fetus. People with the following conditions are good candidates for PGD:
Patients who are over 35 years old.
Patients who want to know the sex of their baby in advance.
Patients who have had repeated miscarriages due to structural chromosomal abnormalities.
Patients who are at risk of transmitting chromosomal abnormalities such as sickle cell disease.
Patients who have failed IVF treatment several times.
Patients suffering from spermatogram disorders.
Patients trying to get pregnant to find matching stem cells for other siblings needing a bone marrow transplant.
Healthy couples who are against termination of pregnancy during pregnancy and want to have a healthy pregnancy from the beginning.
Couples who want to determine the gender of the baby can have personal or medical reasons for doing so.
Medical reasons
Gender determination can prevent the involvement of the fetus with sex-related genetic diseases such as hemophilia or muscular dystrophy. In this way, the transmission of any genetic disease will be prevented.
Personal reasons
Some couples only desire to have a girl or a boy, which gender determination by IVF can help them to achieve their desire. The point that we should point out is that even couples who have no problems They are not fertile, they can choose the sex of their baby through ectopic fertilization.
What is the accuracy and correctness of PGD in choosing the sex of the embryo?
The level of accuracy and correctness of this test is very high and it can be said that it is correctly diagnosed in ninety-nine percent of cases. Making a decision regarding determining the gender of the fetus can be difficult for many couples. For this reason, our advice to couples is to make their final decision before starting the treatment and in this way they can also benefit from the benefits of consultation with the best gynecologists in this center.
Fertility Preservation
The survival rate after cancer has increased significantly in recent decades. However, these treatments also have disadvantages, and patients (or parents in the case of children) should be informed of the long-term complications of oncological treatments and possible options for fertility preservation in these patients. In oncological patients, two special situations often arise: short time to stimulate ovulation and the need not to reach high levels of estradiol. In using embryo freezing methods to preserve the fertility of cancer patients, it is very important to know the couple’s preference for disposal of unused embryos. Until now, embryo freezing has been the only clinically accepted method to preserve the fertility of cancer patients before chemotherapy and/or radiotherapy. The pregnancy rate after thawing is acceptable and depending on the number of available embryos and their quality, it is around 30% per transfer of frozen embryos.
Experimental methods of preserving male fertility and treating male factor infertility
Infertility is a common disease that has insidious effects on infertile individuals, their families, and society that go far beyond the inability to have biological children. Lifestyle changes, infertility treatments, and assisted reproductive technology (ART) are available to help many infertile couples achieve their fertility goals. All of these technologies require that the infertile individual be able to produce at least a small number of functional gametes (eggs or sperm). It is not possible for a person who does not produce gametes to have a biological child. This review focuses on the infertile male and describes several stem cell-based methods and gene therapy approaches that are under investigation and may lead to new fertility treatment options for men with azoospermia.
What do you mean by fertility preservation?
A method used to help preserve a person’s ability to have children. In fact, it is a method of maintaining fertility, which is performed before the start of medical treatment for some diseases that may cause infertility, such as radiation therapy or chemotherapy.
Fertility preservation for women
Fertility preservation using tamoxifen and letrozole in a trial of estrogen-sensitive tumors. Letrozole plus gonadotropin and tamoxifen plus gonadotropin are currently used for fertility preservation in patients with estrogen receptor-positive breast cancer, it is unclear which of the two may lead to improved oocyte function.
Serum biomarkers to determine treatment effects on ovarian reserve in postmenopausal women with breast cancer or mutations.
Ovarian tissue freezing. The study hopes to help develop ovarian tissue freezing and thawing technologies to preserve fertility. The study is open to women undergoing cancer treatment or surgery, or women who have an inherited mutation and are considering risk-reducing surgery.
Fertility preservation for men
Freezing testicular tissue to preserve fertility. Testicular tissue freezing is an experimental procedure in which testicular tissue is recovered and frozen. This technique is intended for young male patients, with the goal that their tissue may be used to restore fertility in the future, when experimental techniques come out of the research pipeline. It is explained in detail on the page related to the type of service.
Infertility Treatment
Infertility is when a couple cannot conceive despite having regular unprotected sex.
1 out of every 7 couples may have difficulty conceiving. About 84% of couples conceive naturally within a year if they have regular unprotected sex (every 2 or 3 days).
For couples who have been trying to conceive for more than 3 years without success, the chance of getting pregnant naturally in the next year is 1 in 4 or less.
Getting help
Some people get pregnant quickly, but for others it may take longer. If you do not get pregnant after a year of trying, it is better to see a specialist doctor.
Women 36 years of age and older, and anyone who already knows they may have fertility problems, should see their health care provider early.
They can investigate common causes of fertility problems and suggest treatments that can help.
Infertility is usually diagnosed when a couple fails to conceive after a year of trying.
There are 2 types of infertility
Primary Infertility: It is about a person who has never had a child in the past and now has trouble getting pregnant.
Secondary infertility: It is about a person who has been pregnant 1 or more times in the past, but now has trouble getting pregnant again.
Infertility treatment
Infertility treatments include
Medical treatment for irregular ovulation: surgical procedures such as treating endometriosis, repairing the fallopian tubes, or removing scarring (adhesions) in the uterus or abdominal cavity.
Assisted fertilization such as intrauterine insemination (IUI) or IVF.
The treatment offered depends on what is causing the fertility problems and what services are available at the clinic you visit.
It is important to choose a private clinic carefully. You can ask a general practitioner for advice and you should make sure that you choose a clinic that is licensed by the Ministry of Health.
While infertility treatment is promising, some infertility treatments such as IVF can cause complications.
Multiple pregnancy
If more than 1 embryo is placed in the uterus as part of IVF treatment, the chance of twins increases. This may not sound like a bad thing, but it significantly increases the risk of complications for you and your babies.
Ectopic pregnancy
If IVF is performed, the risk of ectopic pregnancy increases slightly.
What causes infertility?
There are many possible causes of infertility, and fertility problems can affect either partner. But in a quarter of cases, the cause cannot be identified.
Common causes of infertility include:
Lack of regular ovulation (monthly egg release)
low quality semen
Blocked or damaged fallopian tubes
Endometriosis: where the tissue that acts like the inner lining of the uterus (endometrium) is found outside the uterus.
Risk factors
There are also several factors that can affect fertility, including:
Age: Fertility decreases with age.
Weight: Being overweight or obese (having a BMI of 30 or more) reduces fertility. In women, being overweight or severely underweight can affect ovulation.
Sexually transmitted infections (STIs): Several sexually transmitted diseases, including chlamydia, can affect fertility.
Smoking: Can affect fertility Smoking (including passive smoking) affects your chances of getting pregnant and can reduce the quality of semen.
Alcohol: The safest way is not to drink alcohol at all to minimize the risks to your baby. Drinking too much alcohol can also affect sperm quality.
Environmental factors: Exposure to certain pesticides, solvents, and metals has been shown to affect fertility, especially in men.
Stress: It can affect your relationship with your partner and cause a decrease in sex drive. In severe cases, stress may also affect ovulation and sperm production.
There is no evidence that caffeinated beverages such as tea, coffee, and cola are associated with fertility problems.
Causes of infertility
Infertility can be caused by many reasons. For 1 out of 4 couples, the cause cannot be identified.
Infertility in women
Infertility is usually caused by problems with ovulation (the monthly release of an egg from the ovaries).
Some problems stop the egg from being released altogether, while others prevent the egg from being released during some cycles but not others.
Ovulation problems can be caused by:
polycystic ovary syndrome (PCOS)
Thyroid problems: Both hyperthyroidism and hypothyroidism can prevent ovulation.
Premature ovarian failure: where the ovaries stop working before the age of 40.
Scars from surgery
Pelvic surgery can damage and scar the fallopian tubes that connect the ovaries to the uterus.
Cervical surgery can also sometimes cause scarring or shortening of the cervix (cervix).
Cervical mucus problems
When you’re ovulating, the lining of your cervix becomes thinner so that sperm can swim through it more easily. If there is a problem with the mucus, it can make it more difficult to get pregnant.
Fibroids
A non-cancerous growth called a fibroid in or around the uterus can affect fertility. In some cases, they may prevent a fertilized egg from attaching to the uterus or may block the fallopian tube.
endometriosis
Endometriosis is a condition in which small pieces of the lining of the uterus (endometrium) start to grow in other places, such as the ovaries. It can damage the ovaries or fallopian tubes and cause fertility problems.
Pelvic inflammatory disease
Pelvic inflammatory disease (PID) is an infection of the female upper reproductive tract, which includes the uterus, fallopian tubes, and ovaries. It is often caused by a sexually transmitted infection (STI). PID can damage the fallopian tubes, causing them to become sore and making it impossible for the egg to move into the uterus.
sterilization
Some women who no longer intend to have children choose sterilization. Sterilization involves blocking the fallopian tubes so that the egg cannot reach the uterus. It is rarely reversible, so you will not necessarily be able to have a baby by doing a sterilization reversal.
Medicines and drugs
Side effects of some types of drugs and drugs can affect your fertility. This includes:
Nonsteroidal anti-inflammatory drugs (NSAIDs): Long-term or high-dose use of NSAIDs, such as ibuprofen or aspirin, can make it more difficult to get pregnant.
Chemotherapy: The drugs used for chemotherapy can sometimes cause ovarian failure, which means your ovaries can no longer work properly.
Neuroleptics: Antipsychotic drugs, often used to treat psychosis, can sometimes cause amenorrhea or infertility.
Spironolactone is a type of medicine used to treat fluid retention (edema). Fertility should usually improve about 2 months after discontinuing spironolactone.
Illicit drugs such as marijuana and cocaine can seriously affect fertility and make ovulation more difficult.
Infertility in men
semen and sperm
One of the common causes of infertility in men is poor quality semen (liquid containing sperm) that is ejaculated during sex.
Possible causes of abnormal sperm include:
1. Lack of sperm: You may have very low sperm count or no sperm at all.
2. Sperms that don’t move properly: This makes it harder for the sperm to swim towards the egg.
3. Abnormal sperm: Sperm can sometimes be abnormally shaped, making it harder for them to move and fertilize an egg.
Many cases of abnormal semen are unexplained.
There is a link between increased scrotal temperature and decreased semen quality, but it is unclear whether wearing loose underwear improves fertility.
testicles
The testicles produce and store sperm. If they are damaged, it can seriously affect the quality of your semen.
Damage to the testicles can occur as a result of:
Infection of your testicles.
testicular cancer
Testicular surgery.
A problem with your testicles that you were born with (birth defect): when one or both testicles have not descended into the scrotum (the loose sac of skin that contains your testicles) (undescended testicles).
Damage to your testicles.
Sterilization: Some men choose a vasectomy if they do not want a child or more children.
This involves cutting and sealing off the tubes that carry sperm from your testicles (epididymal death) so that your semen no longer contains sperm. A vasectomy can be reversed, but reversals are usually not successful.
Ejaculation disorders: Some men experience ejaculation problems, which can make it difficult to release semen during sex (ejaculation).
Hypogonadism: Hypogonadism is an abnormally low level of testosterone, the male sex hormone involved in sperm production. Hypogonadism may be caused by a tumor, illegal drug use, or Klinefelter syndrome (a rare syndrome involving an extra female chromosome).
Medicines and drugs: Certain types of drugs can sometimes cause infertility problems. This includes:
Sulfasalazine is an anti-inflammatory drug used to treat diseases such as Crohn’s disease and rheumatoid arthritis. Sulfasalazine can lower sperm count, but the effects are temporary and your sperm count should return to normal when you stop taking it.
Anabolic steroids: Often used illegally to build muscle and improve athletic performance. Long-term abuse of anabolic steroids can reduce sperm count and sperm motility.
Chemotherapy: Drugs used in chemotherapy can sometimes severely reduce sperm production.
Herbal medicines: Some herbal medicines, such as the root extract of the Chinese plant Tripterygium wilfordii, can affect sperm production or reduce the size of your testicles.
Illegal drugs such as marijuana and cocaine can also affect semen quality.
intrauterine insemination
intrauterine insemination (IUI) is a type of artificial insemination and a method of treating infertility. In this procedure, washed and concentrated sperm are placed directly into your uterus when your ovary releases one or more eggs for fertilization.
intrauterine insemination (IUI) treatment
During an intrauterine insemination (IUI) procedure, sperm are placed directly into the uterus using a small catheter. The purpose of this treatment is to improve the chance of conception by increasing the number of healthy sperm that reaches the fallopian tubes when the woman is most fertile.
IUI can be useful for:
Couples experiencing infertility due to medical conditions (such as endometriosis or low sperm count and quality).
Couples with unexplained infertility.
IUI is a widely used treatment option because it is a minimally invasive and low-cost alternative to in vitro fertilization (IVF) and can be easily performed in our clinic.
What to expect in IUI treatment:
At your initial consultation, you’ll meet with one of our fertility specialists to go over your medical history and family planning goals. We will then order diagnostic tests such as a saline infusion ultrasound (SIS) or hysterosalpingogram (HSG) to make sure your fallopian tubes are open and your uterus looks normal. This information is important to help us know which infertility treatment is best for you.
IUI treatment is performed during the ovulation cycle. Usually, patients use fertility drugs such as Clomid to stimulate ovulation. We prescribe your medications and monitor you closely with regular ultrasounds and blood tests to determine the best time for your insemination procedure.
Once your ovulation window is determined, your partner provides a sperm sample to our andrologists, then we perform a special procedure called sperm washing on the samples in the laboratory to obtain the best sperm quality.
Your IUI treatment will be done at the Sirvan infertility treatment center and at the IUI treatment clinic. During this procedure, the doctor first inserts a speculum to view the cervix (opening to the uterus), somewhat like performing a Pap smear. Next, we insert a small catheter (designed specifically for IUI) to place the final sample of semen into your uterus. The process only takes a few minutes and is generally painless. Some women experience mild cramping during the procedure and spotting one to two days after the procedure. After the operation, you can return to your normal daily activities, including intercourse.
Two weeks after IUI, you will take a pregnancy test to check if the procedure was successful. If you are pregnant, we will closely monitor your pregnancy through blood tests and ultrasounds. If you test negative, we will prepare for a new treatment cycle or consider other treatment options.
What is the difference between IUI and IVF?
Through intrauterine insemination (IUI), sperm are inserted directly into the uterus using a speculum. Through in vitro fertilization (IVF), eggs are surgically removed using a needle passed through the back of the vagina, and those eggs are fertilized outside the body.
How long does it take to get pregnant with IUI?
How long does it take to get pregnant using IUI? Since the insemination is done during ovulation, it takes approximately two weeks after the procedure to determine if the treatment was successful after a positive pregnancy test.
What are the chances of pregnancy with IUI?
Pregnancy can occur, but the success rate depends on the location of the blockage. If the blockage is near the ovary, the success rate of IUI is 11.7%. If it is close to the uterus, the chance of success is about 38.1%. If the intended father experiences male factor infertility, the success rate of IUI is about 16.9%.
How does IUI help pregnancy?
IUI works by placing sperm cells directly into your uterus at the time of ovulation, helping the sperm get closer to your egg. This reduces the time and distance the sperm must travel and makes it easier to fertilize the egg.
How painful is the IUI procedure?
IUI is minimally invasive and patients do not even need sedation or anesthesia during the treatment. Patients may experience a mild pinching experience (similar to that experienced during a routine Pap smear test) and some cramping as the catheter passes through the cervix.
Can you choose the gender with IUI?
Microsort is the only method for sex selection IUI intrauterine insemination. Many clinics offer sperm selection by weight, also known as the Erickson method, but this method cannot be compared to micro-sorting technology.
Microinjection IVF
Step by step IVF
On this page you will read:
Start with IVF
Preparation before treatment
IVF injection
Egg retrieval process
Sperm collection
Fetal development
Embryo transfer
freezing
Pregnancy test and pregnancy follow-up
Find a fertility specialist
Resources for IVF patients
Start with IVF
IVF in vitro fertilization step by step:
As a patient at Sirvan Fertility Medicine Center, you can expect to receive the highest quality of care for IVF treatment. Before starting IVF, you will go through a fertility evaluation process. Once you’ve completed that and you and your specialist have decided that IVF is the next step in your fertility journey, you’ll go through the following steps:
Preparation before treatment
IVF injection
Egg retrieval process
Sperm collection
fetal growth
Embryo transfer
Pregnancy test and pregnancy follow-up
Preparation before treatment
Calendar Cycle and Schedule: At the time of your first treatment visit, we ask you to complete the following:
Pre-pregnancy screening tests
Evaluation of the uterine cavity
Consider preconception genetic carrier screening
Sperm analysis (if not already done)
Our nurses will help you plan these things. Our nurses will also create a calendar for your entire course.
IVF injection
Preparation for egg retrieval with IVF injection
The IVF egg retrieval process begins with your doctor prescribing a series of medications (usually ampoules) that help your ovaries produce multiple mature eggs at the same time. Retrieving multiple eggs increases your chances of success because not all eggs are fertilized or develop normally after fertilization. Before starting medications to stimulate the ovaries to produce eggs, your doctor will measure your uterine lining. And the ovaries will be examined for possible follicles or cysts. If the ultrasound is normal, a nurse will check your individual calendar and confirm when you can start medications to stimulate egg growth.
What can you do to improve the quality of your eggs?
To improve the health of your eggs, we recommend a healthy, balanced diet that limits the amount of highly processed foods. We also recommend moderate exercise and a healthy lifestyle.
However, when you start your IVF injections, it’s important not to exercise too much, as this medicine will enlarge your ovaries and too much exercise can twist the ovaries and cut off blood flow.
IVF egg retrieval process
Once your doctor determines that your eggs are ready for retrieval, you will be given another medication (HCG) or (Lupron) 36 hours before the retrieval procedure. This medicine will bring your eggs to final maturity.
The recovery process (puncture) is a short procedure of 15 to 30 minutes that is performed in the operating room. During egg retrieval, using an ultrasound machine, the doctor uses an ultrasound-guided needle to gently remove your eggs from your ovaries. Your doctor will sedate you with an IV during the procedure and you should have little or no discomfort. Because of the anesthesia, you will need to stay in the clinic for an hour to be monitored before going home. You need it to take you home. You should take a full day off from work to rest and recover.
Recovery after egg retrieval
While the procedure is relatively simple, you may experience some pain after IVF egg retrieval, including cramping and a feeling of fullness or pressure. You should also give your body time to rest and heal after the procedure. We advise you to refrain from vigorous physical activity and sexual intercourse for approximately two weeks.
Side effects of egg retrieval
Side effects after egg retrieval can include the following:
mild cramps
Mild bloating
constipation
Breast tenderness
These are all common side effects after egg retrieval and are nothing to worry about. More severe symptoms include:
hip pain
Blood in the urine or heavy vaginal bleeding
Painful urination
Fever over 38 degrees Celsius
If any of these symptoms occur, please contact your doctor immediately.
Does egg retrieval harm your remaining eggs?
Not at all, the process is well-monitored and non-invasive. After the egg retrieval procedure, the doctor will also perform a vaginal examination to make sure that there is no problem or uterine bleeding.
After egg retrieval
During egg retrieval, your doctor extracts follicular fluid from your ovaries. Eggs are released from your ovaries with follicular fluid. One of our technicians will be with your doctor to help you during the procedure. We will collect the follicular fluid in a test tube. We then transfer the follicular fluid to the embryo lab, where one of our embryologists extracts the eggs in a container with specialized media. Then we incubate your eggs in specialized environments so that they can be fertilized and become embryos.
Repeated Abortion Clinic
Recurrent miscarriage refers to cases where the miscarriage has been repeated spontaneously and at least two to three times in a row. Women who have 2 consecutive spontaneous abortions or 2 failed embryo transfers will be candidates for introduction to the repeated abortion treatment clinic.
The frequent abortion clinic of Sirvan infertility treatment center has been established with the aim of providing specialized services to those pregnant mothers with high-risk pregnancies who need special care. The specialists in this clinic, using the most advanced equipment and according to current knowledge, are trying to help pregnant mothers pass this critical period safely and with minimal complications and have a healthy baby. In case of failure of the treatment, the matter will be examined in the specialized team of recurrent miscarriage treatment, including specialists in obstetrics, gynecology, immunology, embryology, and genetics, with the presence of the couple, and a suggested treatment will be provided.
The reasons for frequent miscarriage are very diverse and include:
Hormonal and genetic disorders
Immune system disorders
infection
Blood coagulation disorders
Structural abnormalities of the reproductive system
Cervical insufficiency, if detected, some of them can be treated.
Other factors: Factors such as phospholipid deficiency syndrome, blood sugar disease, thrombosis, smoking, and the presence of some type of antibody in the mother’s body.
The target group of this clinic:
Mothers with chronic diseases such as preeclampsia and eclampsia
Mothers at risk of miscarriage or premature birth
Mothers with multiple pregnancies
Elderly mothers
Mothers who have a history of repeated miscarriages
Mothers who have had a history of unsuccessful ICSI/IVF cycles
Mothers who have a history of giving birth to a baby with abnormalities
Recurrent miscarriage treatment
Treatments for recurrent miscarriage can include lifestyle changes, medications, surgery, or genetic testing to increase the chances of a successful pregnancy.
If you have experienced repeated miscarriages
Gynecologists are generally familiar with these issues and know which tests to perform. However, if the initial tests show nothing, you may be advised to see a reproductive endocrinologist.
Ways to diagnose recurrent miscarriage
Blood tests
Ultrasound
Genetic screening
Hormonal tests
Histogram
hysteroscopy
Endometrial biopsy
When does recurrent miscarriage need to be investigated?
Fortunately, most women will have a successful pregnancy even after two miscarriages. However, if you’ve had three or more early miscarriages in a row or one miscarriage after 12 weeks, talk to your doctor about getting an investigation.
Does IVF help treat recurrent miscarriage?
Three or more miscarriages occur in less than 1% of women. The good news is that in vitro fertilization (IVF) with genetic testing can significantly reduce the risk of miscarriage and increase the chances of a successful pregnancy.
Referral time for recurrent miscarriage treatment
Anyone who has experienced two or more miscarriages should see a reproductive specialist.
RPL test
RPL testing is performed by taking a small sample of POC and checking for chromosomal abnormalities using standard techniques such as karyotyping and fluorescence in situ hybridization. (FISH).
Can an endocrinologist help with abortion?
Once diagnosed, doctors should refer patients to an endocrinologist, preferably one who specializes in preconception and pregnancy. While some miscarriages remain unexplained, doctors have many diagnostic tools at their disposal.
Drug treatment after abortion
If not all of the tissue comes out, a condition known as an incomplete miscarriage, you may need treatment to stop the bleeding and prevent infection. The most common procedure is dilation and curettage (D&C), which involves dilating the cervix and scraping away the lining of the uterus, or endometrium.
Treatment in repeated abortion clinic
If you have had repeated miscarriages, you may be offered a blood test and/or pelvic ultrasound to identify the cause. At Sirvan Recurrent Miscarriage Clinic, we evaluate your blood tests to check the cause of the possibility of repeated miscarriage. Recurrent pregnancy loss (RPL) affects 0.8 to 1.4% of couples and this prevalence increases with age. finds However, the cause is usually unknown, and most treatments are not supported by strong evidence. There are many tests that look for the causes of RPL:
Hormonal status
Sperm morphology and DNA fragmentation
Immunological status
Evaluation of the uterus
Thrombophilia, etc.
Recently, many types of treatment have appeared, most of which do not have good evidence. For example, we can mention the use of anticoagulants, aspirin, corticosteroids, progesterone, antioxidants, and emotional support for couples. It is argued that some methods, such as preimplantation genetic testing for aneuploidy and intracytoplasmic sperm injection, which are morphologically selected, influence the results and contribute to the treatment of RPL.
Sex determination by IVF method
PGD method includes genetic examination and diagnosis of possible embryo disorders before implantation. PGD is used in the investigation of single-gene disorders (molecular PGD), chromosomal abnormalities, pre-implantation screening (PGS), and is also considered the most accurate and complex technique for sex selection. In the PGD method, in vitro fertilization (IVF/ICSI) is takes, by stimulating the ovary, the woman’s eggs are collected and combined with the man’s sperm in the laboratory and an embryo is formed. On the third day of fertilization, when the embryo has between six and eight cells, a small laser cut is made in the embryo’s cell membrane and one of the cells is removed. to be damaged, separates from the other cells. Removing one of these cells does not harm the developing embryo. Each cell in the embryo contains an identical copy of the embryo’s genome It is checked through one of two molecular or cytological methods, and healthy embryos are placed in the mother’s womb.
In the PGD method, by selecting a genetically healthy embryo, the formation and birth of a baby with genetic abnormalities or chromosomal disorders is prevented. On the other hand, an incision made with a laser to check the fetal cells in the fetal membrane (zona pellucida) helps the embryo to implant in the uterus better. The uterus is implanted. At this stage, one should wait for implantation and a positive pregnancy test. Embryos that do not have any genetic problems will be frozen for later use. Meanwhile, the defective embryos will be destroyed. The test process will last about two weeks, which includes the following steps:
Collection of sperm and egg samples from couples
fertility (microinjection)
Three to five days of time for the growth and development of the embryo
One to two weeks to do the test and review the results.
Finally, the embryo with the desired sex will be implanted in the uterus.
Who can benefit from PGD?
One of the most important advantages of doing this test is that it will prevent the transmission of any disease or genetic disorder to the fetus. People with the following conditions are good candidates for PGD:
Patients who are over 35 years old.
Patients who want to know the sex of their baby in advance.
Patients who have had repeated miscarriages due to structural chromosomal abnormalities.
Patients who are at risk of transmitting chromosomal abnormalities such as sickle cell disease.
Patients who have failed IVF treatment several times.
Patients suffering from spermatogram disorders.
Patients trying to get pregnant to find matching stem cells for other siblings needing a bone marrow transplant.
Healthy couples who are against termination of pregnancy during pregnancy and want to have a healthy pregnancy from the beginning.
Couples who want to determine the gender of the baby can have personal or medical reasons for doing so.
Medical reasons
Gender determination can prevent the involvement of the fetus with sex-related genetic diseases such as hemophilia or muscular dystrophy. In this way, the transmission of any genetic disease will be prevented.
Personal reasons
Some couples only desire to have a girl or a boy, which gender determination by IVF can help them to achieve their desire. The point that we should point out is that even couples who have no problems They are not fertile, they can choose the sex of their baby through ectopic fertilization.
What is the accuracy and correctness of PGD in choosing the sex of the embryo?
The level of accuracy and correctness of this test is very high and it can be said that it is correctly diagnosed in ninety-nine percent of cases. Making a decision regarding determining the gender of the fetus can be difficult for many couples. For this reason, our advice to couples is to make their final decision before starting the treatment and in this way they can also benefit from the benefits of consultation with the best gynecologists in this center.